Preclinical Detection of Prions in Blood of Nonhuman Primates Infected with Variant Creutzfeldt-Jakob Disease

Variant Creutzfeldt-Jakob disease (vCJD) is caused by prion infection with bovine spongiform encephalopathy and can be transmitted by blood transfusion. Protein misfolding cyclic amplification (PMCA) can detect prions in blood from vCJD patients with 100% sensitivity and specificity. To determine wh...

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Detalles Bibliográficos
Autores principales: Concha-Marambio, Luis, Chacon, Marcelo A., Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924915/
https://www.ncbi.nlm.nih.gov/pubmed/31855141
http://dx.doi.org/10.3201/eid2601.181423

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