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Global Burden of Small Vessel Disease–Related Brain Changes on MRI Predicts Cognitive and Functional Decline

Cerebral small vessel disease is characterized by a wide range of focal and global brain changes. We used a magnetic resonance imaging segmentation tool to quantify multiple types of small vessel disease–related brain changes and examined their individual and combined predictive value on cognitive a...

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Detalles Bibliográficos
Autores principales: Jokinen, Hanna, Koikkalainen, Juha, Laakso, Hanna M., Melkas, Susanna, Nieminen, Tuomas, Brander, Antti, Korvenoja, Antti, Rueckert, Daniel, Barkhof, Frederik, Scheltens, Philip, Schmidt, Reinhold, Fazekas, Franz, Madureira, Sofia, Verdelho, Ana, Wallin, Anders, Wahlund, Lars-Olof, Waldemar, Gunhild, Chabriat, Hugues, Hennerici, Michael, O’Brien, John, Inzitari, Domenico, Lötjönen, Jyrki, Pantoni, Leonardo, Erkinjuntti, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924941/
https://www.ncbi.nlm.nih.gov/pubmed/31699021
http://dx.doi.org/10.1161/STROKEAHA.119.026170