Active role of elongation factor G in maintaining the mRNA reading frame during translation

During translation, the ribosome moves along the mRNA one codon at a time with the help of elongation factor G (EF-G). Spontaneous changes in the translational reading frame are extremely rare, yet how the precise triplet-wise step is maintained is not clear. Here, we show that the ribosome is prone...

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Detalles Bibliográficos
Autores principales: Peng, Bee-Zen, Bock, Lars V., Belardinelli, Riccardo, Peske, Frank, Grubmüller, Helmut, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924986/
https://www.ncbi.nlm.nih.gov/pubmed/31903418
http://dx.doi.org/10.1126/sciadv.aax8030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924986/
https://www.ncbi.nlm.nih.gov/pubmed/31903418
http://dx.doi.org/10.1126/sciadv.aax8030

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