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Active role of elongation factor G in maintaining the mRNA reading frame during translation
During translation, the ribosome moves along the mRNA one codon at a time with the help of elongation factor G (EF-G). Spontaneous changes in the translational reading frame are extremely rare, yet how the precise triplet-wise step is maintained is not clear. Here, we show that the ribosome is prone...
Autores principales: | Peng, Bee-Zen, Bock, Lars V., Belardinelli, Riccardo, Peske, Frank, Grubmüller, Helmut, Rodnina, Marina V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924986/ https://www.ncbi.nlm.nih.gov/pubmed/31903418 http://dx.doi.org/10.1126/sciadv.aax8030 |
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