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Fidelity of translation initiation is required for coordinated respiratory complex assembly
Mammalian mitochondrial ribosomes are unique molecular machines that translate 11 leaderless mRNAs; however, it is not clear how mitoribosomes initiate translation, since mitochondrial mRNAs lack untranslated regions. Mitochondrial translation initiation shares similarities with prokaryotes, such as...
Autores principales: | Rudler, Danielle L., Hughes, Laetitia A., Perks, Kara L., Richman, Tara R., Kuznetsova, Irina, Ermer, Judith A., Abudulai, Laila N., Shearwood, Anne-Marie J., Viola, Helena M., Hool, Livia C., Siira, Stefan J., Rackham, Oliver, Filipovska, Aleksandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924987/ https://www.ncbi.nlm.nih.gov/pubmed/31903419 http://dx.doi.org/10.1126/sciadv.aay2118 |
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