The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine

We have recently demonstrated that purinergic signaling in bone marrow (BM) microenvironment regulates mobilization of hematopoietic stem progenitor cells (HSPCs), mesenchymal stroma cells (MSCs), endothelial progenitor cells (EPCs), and very small embryonic like stem cells (VSELs) into the peripher...

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Detalles Bibliográficos
Autores principales: Adamiak, Mateusz, Bujko, Kamila, Brzezniakiewicz-Janus, Katarzyna, Kucia, Magda, Ratajczak, Janina, Ratajczak, Mariusz Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925070/
https://www.ncbi.nlm.nih.gov/pubmed/31520298
http://dx.doi.org/10.1007/s12015-019-09918-y

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