Prolactin and its receptor as therapeutic targets in glioblastoma multiforme

Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore their contribution in GBM pathogenesis. We detected PRL and PRLR in all GBM cell lines tested. PRLR activation or overexpressio...

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Detalles Bibliográficos
Autores principales: Asad, Antonela Sofía, Nicola Candia, Alejandro Javier, Gonzalez, Nazareno, Zuccato, Camila Florencia, Abt, Araceli, Orrillo, Santiago Jordi, Lastra, Yael, De Simone, Emilio, Boutillon, Florence, Goffin, Vincent, Seilicovich, Adriana, Pisera, Daniel Alberto, Ferraris, María Jimena, Candolfi, Marianela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925187/
https://www.ncbi.nlm.nih.gov/pubmed/31862900
http://dx.doi.org/10.1038/s41598-019-55860-x

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