Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis

Radiation-induced lung injury (RILI) is one of the most common and fatal complications of thoracic radiotherapy, whereas no effective interventions are available. Andrographolide, an active component extracted from Andrographis paniculate, is prescribed as a treatment for upper respiratory tract inf...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Peng, Shuang, Shan, Xinni, Deng, Guoliang, Shen, Lihong, Sun, Jian, Jiang, Chunhong, Yang, Xiaoling, Chang, Zhigang, Sun, Xinchen, Feng, Fude, Kong, Lingdong, Gu, Yanhong, Guo, Wenjie, Xu, Qiang, Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925222/
https://www.ncbi.nlm.nih.gov/pubmed/31862870
http://dx.doi.org/10.1038/s41419-019-2195-8

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