Cargando…
Treatment evaluation to improve preventing mother to child transmission among women with syphilis
The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. We performed a retrospective analysis of municipal databases of mother-to-child syphilis transmission. Pregnant women with syphilis were included. Group specific...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925227/ https://www.ncbi.nlm.nih.gov/pubmed/31862938 http://dx.doi.org/10.1038/s41598-019-56095-6 |
_version_ | 1783481874921816064 |
---|---|
author | Gong, Tian Shao, Yan Liu, Juning Wu, Qianlan Xu, Rong Sun, Li Peng, Xiaoju |
author_facet | Gong, Tian Shao, Yan Liu, Juning Wu, Qianlan Xu, Rong Sun, Li Peng, Xiaoju |
author_sort | Gong, Tian |
collection | PubMed |
description | The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. We performed a retrospective analysis of municipal databases of mother-to-child syphilis transmission. Pregnant women with syphilis were included. Group specific pregnancy outcomes were analyzed according to treatment. A total of 28 pregnant women were diagnosed with syphilis in 2012; 321 were diagnosed with syphilis in 2018. A prevalence of 0.14% was observed amongst pregnant women in Suzhou city from 2012–2018. Primary treatments included benzathine penicillin, ceftriaxone sodium or erythromycin when patients were allergic to Benzathine penicillin. The treatment coverage was 81.57%, and only 52.86% of pregnant women were adequately treated. Adverse pregnant outcomes were higher amongst untreated women. Expanding early screening coverage and promoting treatment were key to improving pregnancy outcomes amongst women with syphilis. |
format | Online Article Text |
id | pubmed-6925227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-69252272019-12-24 Treatment evaluation to improve preventing mother to child transmission among women with syphilis Gong, Tian Shao, Yan Liu, Juning Wu, Qianlan Xu, Rong Sun, Li Peng, Xiaoju Sci Rep Article The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. We performed a retrospective analysis of municipal databases of mother-to-child syphilis transmission. Pregnant women with syphilis were included. Group specific pregnancy outcomes were analyzed according to treatment. A total of 28 pregnant women were diagnosed with syphilis in 2012; 321 were diagnosed with syphilis in 2018. A prevalence of 0.14% was observed amongst pregnant women in Suzhou city from 2012–2018. Primary treatments included benzathine penicillin, ceftriaxone sodium or erythromycin when patients were allergic to Benzathine penicillin. The treatment coverage was 81.57%, and only 52.86% of pregnant women were adequately treated. Adverse pregnant outcomes were higher amongst untreated women. Expanding early screening coverage and promoting treatment were key to improving pregnancy outcomes amongst women with syphilis. Nature Publishing Group UK 2019-12-20 /pmc/articles/PMC6925227/ /pubmed/31862938 http://dx.doi.org/10.1038/s41598-019-56095-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Gong, Tian Shao, Yan Liu, Juning Wu, Qianlan Xu, Rong Sun, Li Peng, Xiaoju Treatment evaluation to improve preventing mother to child transmission among women with syphilis |
title | Treatment evaluation to improve preventing mother to child transmission among women with syphilis |
title_full | Treatment evaluation to improve preventing mother to child transmission among women with syphilis |
title_fullStr | Treatment evaluation to improve preventing mother to child transmission among women with syphilis |
title_full_unstemmed | Treatment evaluation to improve preventing mother to child transmission among women with syphilis |
title_short | Treatment evaluation to improve preventing mother to child transmission among women with syphilis |
title_sort | treatment evaluation to improve preventing mother to child transmission among women with syphilis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925227/ https://www.ncbi.nlm.nih.gov/pubmed/31862938 http://dx.doi.org/10.1038/s41598-019-56095-6 |
work_keys_str_mv | AT gongtian treatmentevaluationtoimprovepreventingmothertochildtransmissionamongwomenwithsyphilis AT shaoyan treatmentevaluationtoimprovepreventingmothertochildtransmissionamongwomenwithsyphilis AT liujuning treatmentevaluationtoimprovepreventingmothertochildtransmissionamongwomenwithsyphilis AT wuqianlan treatmentevaluationtoimprovepreventingmothertochildtransmissionamongwomenwithsyphilis AT xurong treatmentevaluationtoimprovepreventingmothertochildtransmissionamongwomenwithsyphilis AT sunli treatmentevaluationtoimprovepreventingmothertochildtransmissionamongwomenwithsyphilis AT pengxiaoju treatmentevaluationtoimprovepreventingmothertochildtransmissionamongwomenwithsyphilis |