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Treatment evaluation to improve preventing mother to child transmission among women with syphilis

The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. We performed a retrospective analysis of municipal databases of mother-to-child syphilis transmission. Pregnant women with syphilis were included. Group specific...

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Autores principales: Gong, Tian, Shao, Yan, Liu, Juning, Wu, Qianlan, Xu, Rong, Sun, Li, Peng, Xiaoju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925227/
https://www.ncbi.nlm.nih.gov/pubmed/31862938
http://dx.doi.org/10.1038/s41598-019-56095-6
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author Gong, Tian
Shao, Yan
Liu, Juning
Wu, Qianlan
Xu, Rong
Sun, Li
Peng, Xiaoju
author_facet Gong, Tian
Shao, Yan
Liu, Juning
Wu, Qianlan
Xu, Rong
Sun, Li
Peng, Xiaoju
author_sort Gong, Tian
collection PubMed
description The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. We performed a retrospective analysis of municipal databases of mother-to-child syphilis transmission. Pregnant women with syphilis were included. Group specific pregnancy outcomes were analyzed according to treatment. A total of 28 pregnant women were diagnosed with syphilis in 2012; 321 were diagnosed with syphilis in 2018. A prevalence of 0.14% was observed amongst pregnant women in Suzhou city from 2012–2018. Primary treatments included benzathine penicillin, ceftriaxone sodium or erythromycin when patients were allergic to Benzathine penicillin. The treatment coverage was 81.57%, and only 52.86% of pregnant women were adequately treated. Adverse pregnant outcomes were higher amongst untreated women. Expanding early screening coverage and promoting treatment were key to improving pregnancy outcomes amongst women with syphilis.
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spelling pubmed-69252272019-12-24 Treatment evaluation to improve preventing mother to child transmission among women with syphilis Gong, Tian Shao, Yan Liu, Juning Wu, Qianlan Xu, Rong Sun, Li Peng, Xiaoju Sci Rep Article The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. We performed a retrospective analysis of municipal databases of mother-to-child syphilis transmission. Pregnant women with syphilis were included. Group specific pregnancy outcomes were analyzed according to treatment. A total of 28 pregnant women were diagnosed with syphilis in 2012; 321 were diagnosed with syphilis in 2018. A prevalence of 0.14% was observed amongst pregnant women in Suzhou city from 2012–2018. Primary treatments included benzathine penicillin, ceftriaxone sodium or erythromycin when patients were allergic to Benzathine penicillin. The treatment coverage was 81.57%, and only 52.86% of pregnant women were adequately treated. Adverse pregnant outcomes were higher amongst untreated women. Expanding early screening coverage and promoting treatment were key to improving pregnancy outcomes amongst women with syphilis. Nature Publishing Group UK 2019-12-20 /pmc/articles/PMC6925227/ /pubmed/31862938 http://dx.doi.org/10.1038/s41598-019-56095-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Gong, Tian
Shao, Yan
Liu, Juning
Wu, Qianlan
Xu, Rong
Sun, Li
Peng, Xiaoju
Treatment evaluation to improve preventing mother to child transmission among women with syphilis
title Treatment evaluation to improve preventing mother to child transmission among women with syphilis
title_full Treatment evaluation to improve preventing mother to child transmission among women with syphilis
title_fullStr Treatment evaluation to improve preventing mother to child transmission among women with syphilis
title_full_unstemmed Treatment evaluation to improve preventing mother to child transmission among women with syphilis
title_short Treatment evaluation to improve preventing mother to child transmission among women with syphilis
title_sort treatment evaluation to improve preventing mother to child transmission among women with syphilis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925227/
https://www.ncbi.nlm.nih.gov/pubmed/31862938
http://dx.doi.org/10.1038/s41598-019-56095-6
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