A mitochondrial megachannel resides in monomeric F(1)F(O) ATP synthase

Purified mitochondrial ATP synthase has been shown to form Ca(2+)-activated, large conductance channel activity similar to that of mitochondrial megachannel (MMC) or mitochondrial permeability transition pore (mPTP) but the oligomeric state required for channel formation is being debated. We reconst...

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Detalles Bibliográficos
Autores principales: Mnatsakanyan, Nelli, Llaguno, Marc C., Yang, Youshan, Yan, Yangyang, Weber, Joachim, Sigworth, Fred J., Jonas, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925261/
https://www.ncbi.nlm.nih.gov/pubmed/31862883
http://dx.doi.org/10.1038/s41467-019-13766-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925261/
https://www.ncbi.nlm.nih.gov/pubmed/31862883
http://dx.doi.org/10.1038/s41467-019-13766-2

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