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Adenovectors encoding RSV-F protein induce durable and mucosal immunity in macaques after two intramuscular administrations

Respiratory Syncytial Virus (RSV) can cause severe respiratory disease, yet a licensed vaccine is not available. We determined the immunogenicity of two homologous and one heterologous intramuscular prime-boost vaccination regimens using replication-incompetent adenoviral vectors of human serotype 2...

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Detalles Bibliográficos
Autores principales: Salisch, N. C., Izquierdo Gil, A., Czapska-Casey, D. N., Vorthoren, L., Serroyen, J., Tolboom, J., Saeland, E., Schuitemaker, H., Zahn, R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925274/
https://www.ncbi.nlm.nih.gov/pubmed/31885877
http://dx.doi.org/10.1038/s41541-019-0150-4