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Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis
Non-alcoholic steatohepatitis (NASH), characterized by chronic inflammation and fibrosis, is predicted to be the leading cause of cirrhosis and hepatocellular carcinoma (HCC) in the next decade. Although recent evidence suggests the importance of fibrosis as the strongest determinant of HCC developm...
Autores principales: | Asakawa, Masahiro, Itoh, Michiko, Suganami, Takayoshi, Sakai, Takeru, Kanai, Sayaka, Shirakawa, Ibuki, Yuan, Xunmei, Hatayama, Tomomi, Shimada, Shu, Akiyama, Yoshimitsu, Fujiu, Katsuhito, Inagaki, Yutaka, Manabe, Ichiro, Yamaoka, Shoji, Yamada, Tetsuya, Tanaka, Shinji, Ogawa, Yoshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925281/ https://www.ncbi.nlm.nih.gov/pubmed/31862949 http://dx.doi.org/10.1038/s41598-019-56039-0 |
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