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Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis

Non-alcoholic steatohepatitis (NASH), characterized by chronic inflammation and fibrosis, is predicted to be the leading cause of cirrhosis and hepatocellular carcinoma (HCC) in the next decade. Although recent evidence suggests the importance of fibrosis as the strongest determinant of HCC developm...

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Detalles Bibliográficos
Autores principales: Asakawa, Masahiro, Itoh, Michiko, Suganami, Takayoshi, Sakai, Takeru, Kanai, Sayaka, Shirakawa, Ibuki, Yuan, Xunmei, Hatayama, Tomomi, Shimada, Shu, Akiyama, Yoshimitsu, Fujiu, Katsuhito, Inagaki, Yutaka, Manabe, Ichiro, Yamaoka, Shoji, Yamada, Tetsuya, Tanaka, Shinji, Ogawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925281/
https://www.ncbi.nlm.nih.gov/pubmed/31862949
http://dx.doi.org/10.1038/s41598-019-56039-0

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