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Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation
Mitochondria are essential organelles whose function is upheld by their dynamic nature. This plasticity is mediated by large dynamin-related GTPases, called mitofusins in the case of fusion between two mitochondrial outer membranes. Fusion requires ubiquitylation, attached to K398 in the yeast mitof...
Autores principales: | Schuster, Ramona, Anton, Vincent, Simões, Tânia, Altin, Selver, den Brave, Fabian, Hermanns, Thomas, Hospenthal, Manuela, Komander, David, Dittmar, Gunnar, Dohmen, R Jürgen, Escobar-Henriques, Mafalda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925385/ https://www.ncbi.nlm.nih.gov/pubmed/31857350 http://dx.doi.org/10.26508/lsa.201900476 |
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