Cargando…
Electromagnetic field treatment increases purinergic receptor P2X7 expression and activates its downstream Akt/GSK3β/β-catenin axis in mesenchymal stem cells under osteogenic induction
BACKGROUND: Imbalance in bone formation and resorption is a crucial component of the pathological process leading to osteoporosis. Electromagnetic fields (EMFs) have been reported to be beneficial to osteogenesis, although the exact mechanism has not been fully clarified. Purinergic receptor P2X7 is...
Autores principales: | Zhang, Yingchi, Li, Wenkai, Liu, Chaoxu, Yan, Jiyuan, Yuan, Xuefeng, Wang, Wei, Wang, Huaixi, Wu, Hua, Yang, Yong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925409/ https://www.ncbi.nlm.nih.gov/pubmed/31864409 http://dx.doi.org/10.1186/s13287-019-1497-1 |
Ejemplares similares
-
Highly‐expressed P2X7 receptor promotes growth and metastasis of human HOS/MNNG osteosarcoma cells via PI3K/Akt/GSK3β/β‐catenin and mTOR/HIF1α/VEGF signaling
por: Zhang, Yingchi, et al.
Publicado: (2019) -
PSAT1 positively regulates the osteogenic lineage differentiation of periodontal ligament stem cells through the ATF4/PSAT1/Akt/GSK3β/β-catenin axis
por: Jia, Linglu, et al.
Publicado: (2023) -
Hydrogel-hydroxyapatite-monomeric collagen type-I scaffold with low-frequency electromagnetic field treatment enhances osteochondral repair in rabbits
por: Yan, Jiyuan, et al.
Publicado: (2021) -
Gas6/Axl Axis Contributes to Chemoresistance and Metastasis in Breast Cancer through Akt/GSK-3β/β-catenin Signaling
por: Wang, Cun, et al.
Publicado: (2016) -
Extremely low frequency electromagnetic fields promote mesenchymal stem cell migration by increasing intracellular Ca(2+) and activating the FAK/Rho GTPases signaling pathways in vitro
por: Zhang, Yingchi, et al.
Publicado: (2018)