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The next generation of biopanning: next gen sequencing improves analysis of bacterial display libraries

BACKGROUND: Bacterial surface display libraries are a popular tool for novel ligand discovery due to their ease of manipulation and rapid growth rates. These libraries typically express a scaffold protein embedded within the outer membrane with a short, surface-exposed peptide that is either termina...

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Detalles Bibliográficos
Autores principales: Stellwagen, Sarah D., Sarkes, Deborah A., Adams, Bryn L., Hunt, Mia A., Renberg, Rebecca L., Hurley, Margaret M., Stratis-Cullum, Dimitra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925417/
https://www.ncbi.nlm.nih.gov/pubmed/31864334
http://dx.doi.org/10.1186/s12896-019-0577-8