Osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces

BACKGROUND: The goal of this study is to obtain basic information to improve the bone adhesion of silica components, which are used as the main ingredient in glass ionomer cement (GIC). To achieve this, nanorod hydroxyapatite (nHA) was grafted to the surface of silica cover glass. Surface analysis c...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, So Jung, Gupta, Kailash Chandra, Kim, Hun, Kim, Sukyoung, Kang, Inn-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925421/
https://www.ncbi.nlm.nih.gov/pubmed/31890270
http://dx.doi.org/10.1186/s40824-019-0178-6
_version_ 1783481909494415360
author Park, So Jung
Gupta, Kailash Chandra
Kim, Hun
Kim, Sukyoung
Kang, Inn-Kyu
author_facet Park, So Jung
Gupta, Kailash Chandra
Kim, Hun
Kim, Sukyoung
Kang, Inn-Kyu
author_sort Park, So Jung
collection PubMed
description BACKGROUND: The goal of this study is to obtain basic information to improve the bone adhesion of silica components, which are used as the main ingredient in glass ionomer cement (GIC). To achieve this, nanorod hydroxyapatite (nHA) was grafted to the surface of silica cover glass. Surface analysis confirmed nHA was joined to the glass surface and biocompatibility with osteoblasts was investigated. RESULTS: The grafting of nHA on the surface of slide cover glass (Glass) was confirmed by X-ray photoelectron spectroscopy (XPS) and contact angle (θ) measurement. MC3T3-E1 cells were more stretched out on the nHA-grafted cover glass (Glass-nHA) in comparison to the Glass. In addition, the Glass-nHA was more bioactive in supporting the proliferation of MC3T3-E1 cells in comparison to cells seeded on the Glass. CONCLUSION: The Glass-nHA was to be highly bioactive and this might be useful information for property modification of GIC.
format Online
Article
Text
id pubmed-6925421
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-69254212019-12-30 Osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces Park, So Jung Gupta, Kailash Chandra Kim, Hun Kim, Sukyoung Kang, Inn-Kyu Biomater Res Research Article BACKGROUND: The goal of this study is to obtain basic information to improve the bone adhesion of silica components, which are used as the main ingredient in glass ionomer cement (GIC). To achieve this, nanorod hydroxyapatite (nHA) was grafted to the surface of silica cover glass. Surface analysis confirmed nHA was joined to the glass surface and biocompatibility with osteoblasts was investigated. RESULTS: The grafting of nHA on the surface of slide cover glass (Glass) was confirmed by X-ray photoelectron spectroscopy (XPS) and contact angle (θ) measurement. MC3T3-E1 cells were more stretched out on the nHA-grafted cover glass (Glass-nHA) in comparison to the Glass. In addition, the Glass-nHA was more bioactive in supporting the proliferation of MC3T3-E1 cells in comparison to cells seeded on the Glass. CONCLUSION: The Glass-nHA was to be highly bioactive and this might be useful information for property modification of GIC. BioMed Central 2019-12-21 /pmc/articles/PMC6925421/ /pubmed/31890270 http://dx.doi.org/10.1186/s40824-019-0178-6 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Park, So Jung
Gupta, Kailash Chandra
Kim, Hun
Kim, Sukyoung
Kang, Inn-Kyu
Osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces
title Osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces
title_full Osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces
title_fullStr Osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces
title_full_unstemmed Osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces
title_short Osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces
title_sort osteoblast behaviours on nanorod hydroxyapatite-grafted glass surfaces
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925421/
https://www.ncbi.nlm.nih.gov/pubmed/31890270
http://dx.doi.org/10.1186/s40824-019-0178-6
work_keys_str_mv AT parksojung osteoblastbehavioursonnanorodhydroxyapatitegraftedglasssurfaces
AT guptakailashchandra osteoblastbehavioursonnanorodhydroxyapatitegraftedglasssurfaces
AT kimhun osteoblastbehavioursonnanorodhydroxyapatitegraftedglasssurfaces
AT kimsukyoung osteoblastbehavioursonnanorodhydroxyapatitegraftedglasssurfaces
AT kanginnkyu osteoblastbehavioursonnanorodhydroxyapatitegraftedglasssurfaces

Ejemplares similares