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Cancer-associated fibroblast-derived exosomal microRNA-98-5p promotes cisplatin resistance in ovarian cancer by targeting CDKN1A

BACKGROUND: Ovarian cancer (OC) is a gynecological malignancy with a high mortality. Cisplatin-based treatment is the typical treatment regimen for OC patients; however, it may cause unfavorable resistance. The current study intends to explore the function of cancer-associated fibroblast (CAF)-deriv...

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Detalles Bibliográficos
Autores principales: Guo, Hua, Ha, Chunfang, Dong, Hui, Yang, Zhijuan, Ma, Yuan, Ding, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925473/
https://www.ncbi.nlm.nih.gov/pubmed/31889899
http://dx.doi.org/10.1186/s12935-019-1051-3