Gene therapy-emulating small molecule treatments in cystic fibrosis airway epithelial cells and patients

BACKGROUND: Several small molecule corrector and potentiator drugs have recently been licensed for Cystic Fibrosis (CF) therapy. However, other aspects of the disease, especially inflammation, are less effectively treated by these drugs. We hypothesized that small molecule drugs could function eithe...

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Detalles Bibliográficos
Autores principales: Yang, Q., Soltis, A. R., Sukumar, G., Zhang, X., Caohuy, H., Freedy, J., Dalgard, C. L., Wilkerson, M. D., Pollard, H. B., Pollard, B. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925517/
https://www.ncbi.nlm.nih.gov/pubmed/31864360
http://dx.doi.org/10.1186/s12931-019-1214-8

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