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LRRK2 regulation of immune-pathways and inflammatory disease
Mutations in the leucine-rich-repeat kinase 2 (LRRK2) gene are associated with familial and sporadic cases of Parkinson's disease but are also found in immune-related disorders such as inflammatory bowel disease, tuberculosis and leprosy. LRRK2 is highly expressed in immune cells and has been f...
Autores principales: | Wallings, Rebecca L., Tansey, Malú G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925522/ https://www.ncbi.nlm.nih.gov/pubmed/31769472 http://dx.doi.org/10.1042/BST20180463 |
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