Cargando…
Chloride transporters and channels in β-cell physiology: revisiting a 40-year-old model
It is accepted that insulin-secreting β-cells release insulin in response to glucose even in the absence of functional ATP-sensitive K(+) (K(ATP))-channels, which play a central role in a ‘consensus model’ of secretion broadly accepted and widely reproduced in textbooks. A major shortcoming of this...
Autores principales: | Di Fulvio, Mauricio, Aguilar-Bryan, Lydia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925527/ https://www.ncbi.nlm.nih.gov/pubmed/31697318 http://dx.doi.org/10.1042/BST20190513 |
Ejemplares similares
-
ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies
por: Poroca, Diogo R., et al.
Publicado: (2017) -
Loss of Slc12a2 specifically in pancreatic β-cells drives metabolic syndrome in mice
por: Abdelgawad, Rana, et al.
Publicado: (2022) -
The Arabidopsis Thylakoid Chloride Channel AtCLCe Functions in Chloride Homeostasis and Regulation of Photosynthetic Electron Transport
por: Herdean, Andrei, et al.
Publicado: (2016) -
Glutamate transporters have a chloride channel with two hydrophobic gates
por: Chen, Ichia, et al.
Publicado: (2021) -
Increased Slc12a1 expression in β-cells and improved glucose disposal in Slc12a2 heterozygous mice
por: Alshahrani, Saeed, et al.
Publicado: (2015)