Cargando…

Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors

Coronary artery disease (CAD) is more frequent among individuals with dysglycemia. Preventive interventions for diabetes can improve cardiometabolic risk factors (CRFs), but it is unclear whether the benefits on CRFs are similar for individuals at different genetic risk for CAD. We built a 201-varia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Merino, Jordi, Jablonski, Kathleen A., Mercader, Josep M., Kahn, Steven E., Chen, Ling, Harden, Maegan, Delahanty, Linda M., Araneta, Maria Rosario G., Walford, Geoffrey A., Jacobs, Suzanne B.R., Ibebuogu, Uzoma N., Franks, Paul W., Knowler, William C., Florez, Jose C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2020
Materias:	Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925585/ https://www.ncbi.nlm.nih.gov/pubmed/31636172 http://dx.doi.org/10.2337/db19-0097

Ejemplares similares

Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials
por: Papandonatos, George D., et al.
Publicado: (2015)

Metabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program
por: Walford, Geoffrey A., et al.
Publicado: (2016)

A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians
por: Piaggi, Paolo, et al.
Publicado: (2017)

A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes
por: Mercader, Josep M., et al.
Publicado: (2017)

The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium
por: Srinivasan, Shylaja, et al.
Publicado: (2021)

Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits
por: Brotman, Sarah M., et al.
Publicado: (2023)

Greater Impact of Melanocortin-4 Receptor Deficiency on Rates of Growth and Risk of Type 2 Diabetes During Childhood Compared With Adulthood in Pima Indians
por: Thearle, Marie S., et al.
Publicado: (2012)

Plasma MicroRNA Signature of Alcohol Consumption: The Rotterdam Study
por: Karabegović, Irma, et al.
Publicado: (2022)

Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish
por: Axton, Elizabeth R, et al.
Publicado: (2019)

Pathways Targeted by Antidiabetes Drugs Are Enriched for Multiple Genes Associated With Type 2 Diabetes Risk
por: Segrè, Ayellet V., et al.
Publicado: (2015)

Metabolomic Changes in Serum of Children with Different Clinical Diagnoses of Malnutrition(1)(2)(3)
por: Di Giovanni, Valeria, et al.
Publicado: (2016)

Metabolic Footprinting of Fermented Milk Consumption in Serum of Healthy Men
por: Pimentel, Grégory, et al.
Publicado: (2018)

The Plasma Proteome Is Associated with Anthropometric Status of Undernourished Nepalese School-Aged Children(1)(2)(3)
por: Lee, Sun Eun, et al.
Publicado: (2017)

Identification of Milk and Cheese Intake Biomarkers in Healthy Adults Reveals High Interindividual Variability of Lewis System–Related Oligosaccharides
por: Pimentel, Grégory, et al.
Publicado: (2020)

Personalized Profiling Reveals Donor- and Lactation-Specific Trends in the Human Milk Proteome and Peptidome
por: Zhu, Jing, et al.
Publicado: (2021)

Urine Metabolite Profiles and Nutrient Intake Based on 4-Day Weighed Food Diary in Habitual Vegans, Vegetarians, and Omnivores
por: Lindqvist, Helen M, et al.
Publicado: (2020)

DHA Supplementation Attenuates Inflammation-Associated Gene Expression in the Mammary Gland of Lactating Mothers Who Deliver Preterm
por: Adams, Joselyn M, et al.
Publicado: (2022)

ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes
por: Baier, Leslie J., et al.
Publicado: (2015)

Genetic Variation at the Sulfonylurea Receptor, Type 2 Diabetes, and Coronary Heart Disease
por: Emdin, Connor A., et al.
Publicado: (2017)

A Genome-Wide Association Study in American Indians Implicates DNER as a Susceptibility Locus for Type 2 Diabetes
por: Hanson, Robert L., et al.
Publicado: (2014)

A Polygenic Score for Type 2 Diabetes Risk Is Associated With Both the Acute and Sustained Response to Sulfonylureas
por: Li, Josephine H., et al.
Publicado: (2021)

A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts
por: Tuomisto, Karolina, et al.
Publicado: (2022)

Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection
por: Vassy, Jason L., et al.
Publicado: (2014)

Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering
por: Powe, Camille E., et al.
Publicado: (2021)

Genetic Determinants of Glycemic Traits and the Risk of Gestational Diabetes Mellitus
por: Powe, Camille E., et al.
Publicado: (2018)

Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity
por: Keildson, Sarah, et al.
Publicado: (2014)

Monocyte miRNAs Are Associated With Type 2 Diabetes
por: Parker, Daniel C., et al.
Publicado: (2022)

A Fecal Metabolite Signature of Impaired Fasting Glucose: Results From Two Independent Population-Based Cohorts
por: Nogal, Ana, et al.
Publicado: (2023)

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations
por: Chen, Brian H., et al.
Publicado: (2016)

Consistent Directions of Effect for Established Type 2 Diabetes Risk Variants Across Populations: The Population Architecture using Genomics and Epidemiology (PAGE) Consortium
por: Haiman, Christopher A., et al.
Publicado: (2012)

Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study
por: Slieker, Roderick C., et al.
Publicado: (2021)

Molecular Signatures Differentiate Immune States in Type 1 Diabetic Families
por: Chen, Yi-Guang, et al.
Publicado: (2014)

Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits
por: Billings, Liana K., et al.
Publicado: (2012)

Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy
por: Williams, Winfred W., et al.
Publicado: (2012)

Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling
por: Roberts, Geoffrey P., et al.
Publicado: (2019)

No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
por: Scott, Robert A., et al.
Publicado: (2012)

Phenotypic and Genetic Characterization of Lower LDL Cholesterol and Increased Type 2 Diabetes Risk in the UK Biobank
por: Klimentidis, Yann C., et al.
Publicado: (2020)

MicroRNA-29 Fine-tunes the Expression of Key FOXA2-Activated Lipid Metabolism Genes and Is Dysregulated in Animal Models of Insulin Resistance and Diabetes
por: Kurtz, C. Lisa, et al.
Publicado: (2014)

Contribution of Common Genetic Variation to the Risk of Type 2 Diabetes in the Mexican Mestizo Population
por: Gamboa-Meléndez, Marco Alberto, et al.
Publicado: (2012)

FTO Genotype, Vitamin D Status, and Weight Gain During Childhood
por: Lourenço, Barbara H., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_sbg2beg1rgq7iv6j32cumu2uh9