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An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement

The clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephro...

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Autores principales: Aydın Köker, Sultan, Koker, Alper, Köksoy, Adem Yasin, Kayadibi, Yasemin, Gül Şiraz, Ülkü, Tekin, Emine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925800/
https://www.ncbi.nlm.nih.gov/pubmed/31885952
http://dx.doi.org/10.1155/2019/2802141
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author Aydın Köker, Sultan
Koker, Alper
Köksoy, Adem Yasin
Kayadibi, Yasemin
Gül Şiraz, Ülkü
Tekin, Emine
author_facet Aydın Köker, Sultan
Koker, Alper
Köksoy, Adem Yasin
Kayadibi, Yasemin
Gül Şiraz, Ülkü
Tekin, Emine
author_sort Aydın Köker, Sultan
collection PubMed
description The clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephromegaly without acute renal failure (ARF) as the first manifestation. A 30-month-old boy was admitted to the department of pediatric nephrology exhibiting abdominal distension. Physical examination revealed bilateral renal palpation up to the inguinal region. Elevated lactate dehydrogenase (LDH) levels were detected in his blood. Bilateral diffuse enlarged kidneys with increased hypoechogenicity were found on abdominal ultrasonography. In the next step, contrast-enhanced computed tomography showed diffusely enlarged kidneys, which were compressing the intestinal bowels and midline structures. Renal biopsy demonstrated precursor T-LBL. We wish to report our patient with renal T-LBL presenting with diffuse renal enlargement, which has rarely been reported in the literature.
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spelling pubmed-69258002019-12-29 An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement Aydın Köker, Sultan Koker, Alper Köksoy, Adem Yasin Kayadibi, Yasemin Gül Şiraz, Ülkü Tekin, Emine Case Rep Hematol Case Report The clinical presentation of Non-Hodgkin lymphoma (NHL) is frequently associated with the involvement of the abdomen and mediastinal lymphadenopathies, but rarely the kidney, ovaries, and testicles. Here, we report a rare case of T-cell lymphoblastic lymphoma (T-LBL) presenting with bilateral nephromegaly without acute renal failure (ARF) as the first manifestation. A 30-month-old boy was admitted to the department of pediatric nephrology exhibiting abdominal distension. Physical examination revealed bilateral renal palpation up to the inguinal region. Elevated lactate dehydrogenase (LDH) levels were detected in his blood. Bilateral diffuse enlarged kidneys with increased hypoechogenicity were found on abdominal ultrasonography. In the next step, contrast-enhanced computed tomography showed diffusely enlarged kidneys, which were compressing the intestinal bowels and midline structures. Renal biopsy demonstrated precursor T-LBL. We wish to report our patient with renal T-LBL presenting with diffuse renal enlargement, which has rarely been reported in the literature. Hindawi 2019-12-10 /pmc/articles/PMC6925800/ /pubmed/31885952 http://dx.doi.org/10.1155/2019/2802141 Text en Copyright © 2019 Sultan Aydın Köker et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Aydın Köker, Sultan
Koker, Alper
Köksoy, Adem Yasin
Kayadibi, Yasemin
Gül Şiraz, Ülkü
Tekin, Emine
An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_full An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_fullStr An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_full_unstemmed An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_short An Unusual Presentation of T-Cell Lymphoblastic Lymphoma with Isolated Renal Involvement
title_sort unusual presentation of t-cell lymphoblastic lymphoma with isolated renal involvement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925800/
https://www.ncbi.nlm.nih.gov/pubmed/31885952
http://dx.doi.org/10.1155/2019/2802141
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