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Cathepsin B pH-Dependent Activity Is Involved in Lysosomal Dysregulation in Atrophic Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is characterized by retinal pigment epithelial (RPE) cell dysfunction beginning at early stages of the disease. The lack of an appropriate in vitro model is a major limitation in understanding the mechanisms leading to the occurrence of AMD. This study compared...

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Detalles Bibliográficos
Autores principales:	Voisin, Audrey, Monville, Christelle, Plancheron, Alexandra, Béré, Emile, Gaillard, Afsaneh, Leveziel, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925809/ https://www.ncbi.nlm.nih.gov/pubmed/31885803 http://dx.doi.org/10.1155/2019/5637075

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