Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study

This study aimed to develop a selective, simple, and sensitive HPLC-MS/MS method for the simultaneous determination of schisandrin and promethazine (PMZ) with its metabolite in rat plasma, which was further used for a pharmacokinetic herb-drug interaction study. HPLC-MS/MS analyses were performed on...

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Detalles Bibliográficos
Autores principales: Gao, Sijia, Zhou, Xuelin, Lang, Liwei, Liu, Honghong, Li, Jianyu, Li, Haotian, Wei, Shizhang, Wang, Dan, Xu, Zhuo, Cai, Huadan, Zhao, Yanling, Zou, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925819/
https://www.ncbi.nlm.nih.gov/pubmed/31885590
http://dx.doi.org/10.1155/2019/3497045

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