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HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo
BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL) and the neurological disorder HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The exact mechanism(s) through which latency and disease progression are regulated...
Autores principales: | Martinez, Michael P., Cheng, Xiaogang, Joseph, Ancy, Al-Saleem, Jacob, Panfil, Amanda R., Palettas, Marilly, Dirksen, Wessel P., Ratner, Lee, Green, Patrick L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925871/ https://www.ncbi.nlm.nih.gov/pubmed/31864373 http://dx.doi.org/10.1186/s12977-019-0507-9 |
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