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Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases

Female infertility impacts the quality of life and well-being of affected individuals and couples. Female reproductive diseases, such as primary ovarian insufficiency, polycystic ovary syndrome, endometriosis, fallopian tube obstruction, and Asherman syndrome, can induce infertility. In recent years...

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Detalles Bibliográficos
Autores principales: Zhao, Yun-xia, Chen, Shao-rong, Su, Ping-ping, Huang, Feng-huang, Shi, Yan-chuan, Shi, Qi-yang, Lin, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925937/
https://www.ncbi.nlm.nih.gov/pubmed/31885630
http://dx.doi.org/10.1155/2019/9071720
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author Zhao, Yun-xia
Chen, Shao-rong
Su, Ping-ping
Huang, Feng-huang
Shi, Yan-chuan
Shi, Qi-yang
Lin, Shu
author_facet Zhao, Yun-xia
Chen, Shao-rong
Su, Ping-ping
Huang, Feng-huang
Shi, Yan-chuan
Shi, Qi-yang
Lin, Shu
author_sort Zhao, Yun-xia
collection PubMed
description Female infertility impacts the quality of life and well-being of affected individuals and couples. Female reproductive diseases, such as primary ovarian insufficiency, polycystic ovary syndrome, endometriosis, fallopian tube obstruction, and Asherman syndrome, can induce infertility. In recent years, translational medicine has developed rapidly, and clinical researchers are focusing on the treatment of female infertility using novel approaches. Owing to the advantages of convenient samples, abundant sources, and avoidable ethical issues, mesenchymal stem cells (MSCs) can be applied widely in the clinic. This paper reviews recent advances in using four types of MSCs, bone marrow stromal cells, adipose-derived stem cells, menstrual blood mesenchymal stem cells, and umbilical cord mesenchymal stem cells. Each of these have been used for the treatment of ovarian and uterine diseases, and provide new approaches for the treatment of female infertility.
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spelling pubmed-69259372019-12-29 Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases Zhao, Yun-xia Chen, Shao-rong Su, Ping-ping Huang, Feng-huang Shi, Yan-chuan Shi, Qi-yang Lin, Shu Stem Cells Int Review Article Female infertility impacts the quality of life and well-being of affected individuals and couples. Female reproductive diseases, such as primary ovarian insufficiency, polycystic ovary syndrome, endometriosis, fallopian tube obstruction, and Asherman syndrome, can induce infertility. In recent years, translational medicine has developed rapidly, and clinical researchers are focusing on the treatment of female infertility using novel approaches. Owing to the advantages of convenient samples, abundant sources, and avoidable ethical issues, mesenchymal stem cells (MSCs) can be applied widely in the clinic. This paper reviews recent advances in using four types of MSCs, bone marrow stromal cells, adipose-derived stem cells, menstrual blood mesenchymal stem cells, and umbilical cord mesenchymal stem cells. Each of these have been used for the treatment of ovarian and uterine diseases, and provide new approaches for the treatment of female infertility. Hindawi 2019-12-06 /pmc/articles/PMC6925937/ /pubmed/31885630 http://dx.doi.org/10.1155/2019/9071720 Text en Copyright © 2019 Yun-xia Zhao et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zhao, Yun-xia
Chen, Shao-rong
Su, Ping-ping
Huang, Feng-huang
Shi, Yan-chuan
Shi, Qi-yang
Lin, Shu
Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases
title Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases
title_full Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases
title_fullStr Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases
title_full_unstemmed Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases
title_short Using Mesenchymal Stem Cells to Treat Female Infertility: An Update on Female Reproductive Diseases
title_sort using mesenchymal stem cells to treat female infertility: an update on female reproductive diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925937/
https://www.ncbi.nlm.nih.gov/pubmed/31885630
http://dx.doi.org/10.1155/2019/9071720
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