Dataset on the formation of Thioredoxin interacting protein (Txnip) containing redox sensitive high molecular weight nucleoprotein complexes

This dataset is supplementary to the submitted research by Ref. [1]. RNAs were extracted from high molecular weight complexes, prepared with 100 kDa filtration of HEK293 Tet-on cells stably transfected with either F-HA-Txnip-V5-His or control vector. Cells were stimulated with 1 μg/mL doxycycline for 24 h, followed by overnight stimulation with 100 μM 4-thiouridine (4sU), 20 mM glucose, and 1 μM bortezomib for 14h. The extracted RNAs from Txnip overexpressing cells compared with control cells was analyzed by RNA-seq. Differentially expressed mRNAs, long noncoding RNAs (lncRNA) and transcripts of uncertain coding potential (TUCPs) are shown. Gene ontology and KEGG enrichment of these differential expressed RNAs is presented.