Epigenetic Inactivation of SOX30 Is Associated with Male Infertility and Offers a Therapy Target for Non-obstructive Azoospermia

Non-obstructive azoospermia (NOA) is the most severe form of male infertility. However, the etiology of NOA is largely unknown, resulting in a lack of clinical treatments. Here, we performed a comparative genome-wide profiling of DNA methylation and identified SOX30 as the most notably hyper-methyla...

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Detalles Bibliográficos
Autores principales: Han, Fei, Jiang, Xiao, Li, Zhi-ming, Zhuang, Xuan, Zhang, Xi, Ouyang, Wei-ming, Liu, Wen-bin, Mao, Cheng-yi, Chen, Qing, Huang, Chuan-shu, Gao, Fei, Cui, Zhi-hong, Ao, Lin, Li, Yan-feng, Cao, Jia, Liu, Jin-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926170/
https://www.ncbi.nlm.nih.gov/pubmed/31835093
http://dx.doi.org/10.1016/j.omtn.2019.10.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926170/
https://www.ncbi.nlm.nih.gov/pubmed/31835093
http://dx.doi.org/10.1016/j.omtn.2019.10.038

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