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Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report

INTRODUCTION: Laparoscopic liver resection is currently performed as a therapeutic modality in hepatocellular carcinoma (HCC). In an emergency setting such as bleeding or rupture, however it has not been well documented. PRESENTATION OF CASE: We describe a 55-year-old lady who presented to the emerg...

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Autores principales: Khairuddin, Allim, Ong, Guang Hong, Tan, Jun Sam, Johan, Syamim, Hoe, Vee Chuan, Sharif, Mohd Sharifudin, Hayati, Firdaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926279/
https://www.ncbi.nlm.nih.gov/pubmed/31830742
http://dx.doi.org/10.1016/j.ijscr.2019.11.055
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author Khairuddin, Allim
Ong, Guang Hong
Tan, Jun Sam
Johan, Syamim
Hoe, Vee Chuan
Sharif, Mohd Sharifudin
Hayati, Firdaus
author_facet Khairuddin, Allim
Ong, Guang Hong
Tan, Jun Sam
Johan, Syamim
Hoe, Vee Chuan
Sharif, Mohd Sharifudin
Hayati, Firdaus
author_sort Khairuddin, Allim
collection PubMed
description INTRODUCTION: Laparoscopic liver resection is currently performed as a therapeutic modality in hepatocellular carcinoma (HCC). In an emergency setting such as bleeding or rupture, however it has not been well documented. PRESENTATION OF CASE: We describe a 55-year-old lady who presented to the emergency department with epigastric pain and symptoms of anaemia for one day duration. She was normotensive but tachycardic. Blood investigations revealed haemoglobin level of 6.5 g/dL and serum alpha-fetoprotein of 3136 g/dL. Contrast enhanced computed tomography scan revealed ruptured HCC of segment 2 and 3. She underwent emergency laparoscopic resection of the ruptured HCC. The postoperative recovery was uneventful and she was discharged well on postoperative day 7. Histology confirmed a 10 cm ruptured HCC with 3 mm tumour-free resection margin. DISCUSSION: Ruptured HCC is associated with a high mortality rate of 25–75 %. Traditional treatment involves initial stabilization and hemostasis through transarterial embolization followed by staged hepatic resection. However, laparoscopic liver resection has been shown to be superior than open surgery in terms of postoperative outcomes. CONCLUSION: Laparoscopic resection of bleeding HCC is achievable and can be considered in the treatment algorithm of selected patients.
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spelling pubmed-69262792019-12-30 Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report Khairuddin, Allim Ong, Guang Hong Tan, Jun Sam Johan, Syamim Hoe, Vee Chuan Sharif, Mohd Sharifudin Hayati, Firdaus Int J Surg Case Rep Article INTRODUCTION: Laparoscopic liver resection is currently performed as a therapeutic modality in hepatocellular carcinoma (HCC). In an emergency setting such as bleeding or rupture, however it has not been well documented. PRESENTATION OF CASE: We describe a 55-year-old lady who presented to the emergency department with epigastric pain and symptoms of anaemia for one day duration. She was normotensive but tachycardic. Blood investigations revealed haemoglobin level of 6.5 g/dL and serum alpha-fetoprotein of 3136 g/dL. Contrast enhanced computed tomography scan revealed ruptured HCC of segment 2 and 3. She underwent emergency laparoscopic resection of the ruptured HCC. The postoperative recovery was uneventful and she was discharged well on postoperative day 7. Histology confirmed a 10 cm ruptured HCC with 3 mm tumour-free resection margin. DISCUSSION: Ruptured HCC is associated with a high mortality rate of 25–75 %. Traditional treatment involves initial stabilization and hemostasis through transarterial embolization followed by staged hepatic resection. However, laparoscopic liver resection has been shown to be superior than open surgery in terms of postoperative outcomes. CONCLUSION: Laparoscopic resection of bleeding HCC is achievable and can be considered in the treatment algorithm of selected patients. Elsevier 2019-12-03 /pmc/articles/PMC6926279/ /pubmed/31830742 http://dx.doi.org/10.1016/j.ijscr.2019.11.055 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Khairuddin, Allim
Ong, Guang Hong
Tan, Jun Sam
Johan, Syamim
Hoe, Vee Chuan
Sharif, Mohd Sharifudin
Hayati, Firdaus
Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report
title Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report
title_full Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report
title_fullStr Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report
title_full_unstemmed Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report
title_short Emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: A case report
title_sort emergency laparoscopic resection of spontaneous rupture of hepatocellular carcinoma: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926279/
https://www.ncbi.nlm.nih.gov/pubmed/31830742
http://dx.doi.org/10.1016/j.ijscr.2019.11.055
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