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rAAV2-Retro Enables Extensive and High-Efficient Transduction of Lower Motor Neurons following Intramuscular Injection

The motor system controls muscle movement through lower motor neurons in the spinal cord and brainstem. Lower motor neurons are efferent neurons in the central nervous system (CNS) characterized by axonal projections that reach specific targets in the periphery. Lower motor neuron lesions result in...

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Detalles Bibliográficos
Autores principales: Chen, Zhilong, Fan, Guoqing, Li, Anan, Yuan, Jing, Xu, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926343/
https://www.ncbi.nlm.nih.gov/pubmed/31890738
http://dx.doi.org/10.1016/j.omtm.2019.11.006

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