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rAAV2-Retro Enables Extensive and High-Efficient Transduction of Lower Motor Neurons following Intramuscular Injection
The motor system controls muscle movement through lower motor neurons in the spinal cord and brainstem. Lower motor neurons are efferent neurons in the central nervous system (CNS) characterized by axonal projections that reach specific targets in the periphery. Lower motor neuron lesions result in...
Autores principales: | Chen, Zhilong, Fan, Guoqing, Li, Anan, Yuan, Jing, Xu, Tonghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926343/ https://www.ncbi.nlm.nih.gov/pubmed/31890738 http://dx.doi.org/10.1016/j.omtm.2019.11.006 |
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