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Highly Porous Polymer-Derived Bioceramics Based on a Complex Hardystonite Solid Solution

Highly porous bioceramics, based on a complex hardystonite solid solution, were developed from silicone resins and micro-sized oxide fillers fired in air at 950 °C. Besides CaO, SrO, MgO, and ZnO precursors, and the commercial embedded silicone resins, calcium borate was essential in providing the l...

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Autores principales: Elsayed, Hamada, Secco, Michele, Zorzi, Federico, Schuhladen, Katharina, Detsch, Rainer, Boccaccini, Aldo R., Bernardo, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926549/
https://www.ncbi.nlm.nih.gov/pubmed/31801189
http://dx.doi.org/10.3390/ma12233970
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author Elsayed, Hamada
Secco, Michele
Zorzi, Federico
Schuhladen, Katharina
Detsch, Rainer
Boccaccini, Aldo R.
Bernardo, Enrico
author_facet Elsayed, Hamada
Secco, Michele
Zorzi, Federico
Schuhladen, Katharina
Detsch, Rainer
Boccaccini, Aldo R.
Bernardo, Enrico
author_sort Elsayed, Hamada
collection PubMed
description Highly porous bioceramics, based on a complex hardystonite solid solution, were developed from silicone resins and micro-sized oxide fillers fired in air at 950 °C. Besides CaO, SrO, MgO, and ZnO precursors, and the commercial embedded silicone resins, calcium borate was essential in providing the liquid phase upon firing and favouring the formation of an unprecedented hardystonite solid solution, corresponding to the formula (Ca(0.70)Sr(0.30))(2)(Zn(0.72)Mg(0.15)Si(0.13)) (Si(0.85)B(0.15))(2)O(7). Silicone-filler mixtures could be used in the form of thick pastes for direct ink writing of reticulated scaffolds or for direct foaming. The latter shaping option benefited from the use of hydrated calcium borate, which underwent dehydration, with water vapour release, at a low temperature (420 °C). Both scaffolds and foams confirmed the already-obtained phase assemblage, after firing, and exhibited remarkable strength-to-density ratios. Finally, preliminary cell tests excluded any cytotoxicity that could be derived from the formation of a boro-silicate glassy phase.
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spelling pubmed-69265492019-12-24 Highly Porous Polymer-Derived Bioceramics Based on a Complex Hardystonite Solid Solution Elsayed, Hamada Secco, Michele Zorzi, Federico Schuhladen, Katharina Detsch, Rainer Boccaccini, Aldo R. Bernardo, Enrico Materials (Basel) Article Highly porous bioceramics, based on a complex hardystonite solid solution, were developed from silicone resins and micro-sized oxide fillers fired in air at 950 °C. Besides CaO, SrO, MgO, and ZnO precursors, and the commercial embedded silicone resins, calcium borate was essential in providing the liquid phase upon firing and favouring the formation of an unprecedented hardystonite solid solution, corresponding to the formula (Ca(0.70)Sr(0.30))(2)(Zn(0.72)Mg(0.15)Si(0.13)) (Si(0.85)B(0.15))(2)O(7). Silicone-filler mixtures could be used in the form of thick pastes for direct ink writing of reticulated scaffolds or for direct foaming. The latter shaping option benefited from the use of hydrated calcium borate, which underwent dehydration, with water vapour release, at a low temperature (420 °C). Both scaffolds and foams confirmed the already-obtained phase assemblage, after firing, and exhibited remarkable strength-to-density ratios. Finally, preliminary cell tests excluded any cytotoxicity that could be derived from the formation of a boro-silicate glassy phase. MDPI 2019-11-30 /pmc/articles/PMC6926549/ /pubmed/31801189 http://dx.doi.org/10.3390/ma12233970 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Elsayed, Hamada
Secco, Michele
Zorzi, Federico
Schuhladen, Katharina
Detsch, Rainer
Boccaccini, Aldo R.
Bernardo, Enrico
Highly Porous Polymer-Derived Bioceramics Based on a Complex Hardystonite Solid Solution
title Highly Porous Polymer-Derived Bioceramics Based on a Complex Hardystonite Solid Solution
title_full Highly Porous Polymer-Derived Bioceramics Based on a Complex Hardystonite Solid Solution
title_fullStr Highly Porous Polymer-Derived Bioceramics Based on a Complex Hardystonite Solid Solution
title_full_unstemmed Highly Porous Polymer-Derived Bioceramics Based on a Complex Hardystonite Solid Solution
title_short Highly Porous Polymer-Derived Bioceramics Based on a Complex Hardystonite Solid Solution
title_sort highly porous polymer-derived bioceramics based on a complex hardystonite solid solution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926549/
https://www.ncbi.nlm.nih.gov/pubmed/31801189
http://dx.doi.org/10.3390/ma12233970
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