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Environmental Influences on Mammographic Breast Density in California: A Strategy to Reduce Breast Cancer Risk

State legislation in many U.S. states, including California, mandates informing women if they have dense breasts on screening mammography, meaning over half of their breast tissue is comprised of non-adipose tissue. Breast density is important to interpret screening sensitivity and is an established...

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Detalles Bibliográficos
Autores principales: Cohn, Barbara A., Terry, Mary Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926682/
https://www.ncbi.nlm.nih.gov/pubmed/31783496
http://dx.doi.org/10.3390/ijerph16234731
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author Cohn, Barbara A.
Terry, Mary Beth
author_facet Cohn, Barbara A.
Terry, Mary Beth
author_sort Cohn, Barbara A.
collection PubMed
description State legislation in many U.S. states, including California, mandates informing women if they have dense breasts on screening mammography, meaning over half of their breast tissue is comprised of non-adipose tissue. Breast density is important to interpret screening sensitivity and is an established breast cancer risk factor. Environmental chemical exposures may play an important role in this, especially during key windows of susceptibility for breast development: in utero, during puberty, pregnancy, lactation, and the peri-menopause. There is a paucity of research, however, examining whether environmental chemical exposures are associated with mammographic breast density, and even less is known about environmental exposures during windows of susceptibility. Now, with clinical breast density scoring being reported routinely for mammograms, it is possible to find out, especially in California, where there are large study populations that can link environmental exposures during windows of susceptibility to breast density. Density scores are now available throughout the state through electronic medical records. We can link these with environmental chemical exposures via state-wide monitoring. Studying the effects of environmental exposure on breast density may provide valuable monitoring and etiologic data to inform strategies to reduce breast cancer risk.
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spelling pubmed-69266822019-12-24 Environmental Influences on Mammographic Breast Density in California: A Strategy to Reduce Breast Cancer Risk Cohn, Barbara A. Terry, Mary Beth Int J Environ Res Public Health Communication State legislation in many U.S. states, including California, mandates informing women if they have dense breasts on screening mammography, meaning over half of their breast tissue is comprised of non-adipose tissue. Breast density is important to interpret screening sensitivity and is an established breast cancer risk factor. Environmental chemical exposures may play an important role in this, especially during key windows of susceptibility for breast development: in utero, during puberty, pregnancy, lactation, and the peri-menopause. There is a paucity of research, however, examining whether environmental chemical exposures are associated with mammographic breast density, and even less is known about environmental exposures during windows of susceptibility. Now, with clinical breast density scoring being reported routinely for mammograms, it is possible to find out, especially in California, where there are large study populations that can link environmental exposures during windows of susceptibility to breast density. Density scores are now available throughout the state through electronic medical records. We can link these with environmental chemical exposures via state-wide monitoring. Studying the effects of environmental exposure on breast density may provide valuable monitoring and etiologic data to inform strategies to reduce breast cancer risk. MDPI 2019-11-27 2019-12 /pmc/articles/PMC6926682/ /pubmed/31783496 http://dx.doi.org/10.3390/ijerph16234731 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Cohn, Barbara A.
Terry, Mary Beth
Environmental Influences on Mammographic Breast Density in California: A Strategy to Reduce Breast Cancer Risk
title Environmental Influences on Mammographic Breast Density in California: A Strategy to Reduce Breast Cancer Risk
title_full Environmental Influences on Mammographic Breast Density in California: A Strategy to Reduce Breast Cancer Risk
title_fullStr Environmental Influences on Mammographic Breast Density in California: A Strategy to Reduce Breast Cancer Risk
title_full_unstemmed Environmental Influences on Mammographic Breast Density in California: A Strategy to Reduce Breast Cancer Risk
title_short Environmental Influences on Mammographic Breast Density in California: A Strategy to Reduce Breast Cancer Risk
title_sort environmental influences on mammographic breast density in california: a strategy to reduce breast cancer risk
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926682/
https://www.ncbi.nlm.nih.gov/pubmed/31783496
http://dx.doi.org/10.3390/ijerph16234731
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