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Microwave-Assisted Synthesis and Characterization of Poly(L-lysine)-Based Polymer/Carbon Quantum Dot Nanomaterials for Biomedical Purposes
Carbon nanomaterials in the form of quantum dots have a high potential due to their luminescent properties and low cytotoxicity which allows their use in optical probes for use in bioimaging and biodetection. In this article, we present a novel type of nanomaterials and their obtainment method under...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926918/ https://www.ncbi.nlm.nih.gov/pubmed/31766363 http://dx.doi.org/10.3390/ma12233825 |
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author | Janus, Łukasz Piątkowski, Marek Radwan-Pragłowska, Julia |
author_facet | Janus, Łukasz Piątkowski, Marek Radwan-Pragłowska, Julia |
author_sort | Janus, Łukasz |
collection | PubMed |
description | Carbon nanomaterials in the form of quantum dots have a high potential due to their luminescent properties and low cytotoxicity which allows their use in optical probes for use in bioimaging and biodetection. In this article, we present a novel type of nanomaterials and their obtainment method under microwave-assisted conditions using poly(L-lysine) as a raw material. The ready products were characterized over their chemical structure, pH-dependent fluorescence properties and cytotoxicity on human dermal fibroblasts. Moreover, their antioxidant activity as well as ability to biologically active molecules (vitamins) and heavy metal ions detection was evaluated. The results confirmed the obtainment of biocompatible nanomaterials with advanced properties and good water solubility according to sustained development principles. |
format | Online Article Text |
id | pubmed-6926918 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69269182019-12-23 Microwave-Assisted Synthesis and Characterization of Poly(L-lysine)-Based Polymer/Carbon Quantum Dot Nanomaterials for Biomedical Purposes Janus, Łukasz Piątkowski, Marek Radwan-Pragłowska, Julia Materials (Basel) Article Carbon nanomaterials in the form of quantum dots have a high potential due to their luminescent properties and low cytotoxicity which allows their use in optical probes for use in bioimaging and biodetection. In this article, we present a novel type of nanomaterials and their obtainment method under microwave-assisted conditions using poly(L-lysine) as a raw material. The ready products were characterized over their chemical structure, pH-dependent fluorescence properties and cytotoxicity on human dermal fibroblasts. Moreover, their antioxidant activity as well as ability to biologically active molecules (vitamins) and heavy metal ions detection was evaluated. The results confirmed the obtainment of biocompatible nanomaterials with advanced properties and good water solubility according to sustained development principles. MDPI 2019-11-21 /pmc/articles/PMC6926918/ /pubmed/31766363 http://dx.doi.org/10.3390/ma12233825 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Janus, Łukasz Piątkowski, Marek Radwan-Pragłowska, Julia Microwave-Assisted Synthesis and Characterization of Poly(L-lysine)-Based Polymer/Carbon Quantum Dot Nanomaterials for Biomedical Purposes |
title | Microwave-Assisted Synthesis and Characterization of Poly(L-lysine)-Based Polymer/Carbon Quantum Dot Nanomaterials for Biomedical Purposes |
title_full | Microwave-Assisted Synthesis and Characterization of Poly(L-lysine)-Based Polymer/Carbon Quantum Dot Nanomaterials for Biomedical Purposes |
title_fullStr | Microwave-Assisted Synthesis and Characterization of Poly(L-lysine)-Based Polymer/Carbon Quantum Dot Nanomaterials for Biomedical Purposes |
title_full_unstemmed | Microwave-Assisted Synthesis and Characterization of Poly(L-lysine)-Based Polymer/Carbon Quantum Dot Nanomaterials for Biomedical Purposes |
title_short | Microwave-Assisted Synthesis and Characterization of Poly(L-lysine)-Based Polymer/Carbon Quantum Dot Nanomaterials for Biomedical Purposes |
title_sort | microwave-assisted synthesis and characterization of poly(l-lysine)-based polymer/carbon quantum dot nanomaterials for biomedical purposes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926918/ https://www.ncbi.nlm.nih.gov/pubmed/31766363 http://dx.doi.org/10.3390/ma12233825 |
work_keys_str_mv | AT janusłukasz microwaveassistedsynthesisandcharacterizationofpolyllysinebasedpolymercarbonquantumdotnanomaterialsforbiomedicalpurposes AT piatkowskimarek microwaveassistedsynthesisandcharacterizationofpolyllysinebasedpolymercarbonquantumdotnanomaterialsforbiomedicalpurposes AT radwanpragłowskajulia microwaveassistedsynthesisandcharacterizationofpolyllysinebasedpolymercarbonquantumdotnanomaterialsforbiomedicalpurposes |