Cargando…

Rainbow Trout IgM(+) B Cells Preferentially Respond to Thymus-Independent Antigens but Are Activated by CD40L

In the absence of class switch recombination and germinal centers, the mechanisms through which B cells from teleost fish mount extrafollicular immunoglobulin M (IgM) memory responses remains mostly unexplored. In this report, we demonstrate that teleost IgM(+) B cells respond to CD40L, a thymus-dep...

Descripción completa

Detalles Bibliográficos
Autores principales: Granja, Aitor G., Perdiguero, Pedro, Martín-Martín, Alba, Díaz-Rosales, Patricia, Soleto, Irene, Tafalla, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927014/
https://www.ncbi.nlm.nih.gov/pubmed/31921163
http://dx.doi.org/10.3389/fimmu.2019.02902