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Electroacupuncture Improves the Survival Rate and Organ Function in a Rat Model of Hemorrhagic Shock
Electroacupuncture (EA) at ST36 can improve the survival rate in rats after hemorrhagic shock (HS). The current study investigated rats with 60% blood loss. 144 rats were divided into four groups: hemorrhage without fluid resuscitation (HS), EA after hemorrhage without fluid resuscitation (EA), hemo...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927047/ https://www.ncbi.nlm.nih.gov/pubmed/31885667 http://dx.doi.org/10.1155/2019/8371862 |
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author | Zhong, Yuxian Xu, Guochen Wu, Yushou Zhang, Huiping Wang, Haibin Ma, Liqian Zhang, Wenhua Yao, Yongming Wang, Lu Hu, Sen Litscher, Gerhard |
author_facet | Zhong, Yuxian Xu, Guochen Wu, Yushou Zhang, Huiping Wang, Haibin Ma, Liqian Zhang, Wenhua Yao, Yongming Wang, Lu Hu, Sen Litscher, Gerhard |
author_sort | Zhong, Yuxian |
collection | PubMed |
description | Electroacupuncture (EA) at ST36 can improve the survival rate in rats after hemorrhagic shock (HS). The current study investigated rats with 60% blood loss. 144 rats were divided into four groups: hemorrhage without fluid resuscitation (HS), EA after hemorrhage without fluid resuscitation (EA), hemorrhage with delayed resuscitation (DFR), and EA after hemorrhage with delayed resuscitation (EA + DFR). The survival rate and biological parameters 0, 3, 12, and 24 h after HS were investigated. The 24 h survival rate of EA + DFR was significantly higher than that of DFR. 12 h after hemorrhage, the level of mean arterial blood pressure of EA + DFR was significantly higher than that of DFR, and the levels of renal blood flow, intestinal mucosal blood flow, and hepatic blood flow of EA + DFR were also significantly higher than those of DFR. Three hours after hemorrhage, the levels of lactate, PaCO(2), alanine aminotransferase, and creatinine of groups receiving EA were significantly lower than those of non-EA groups, and the levels of pH, PaO(2), and diamine oxidase of groups receiving EA were significantly higher. EA at ST36 can improve the 24 h survival rate and produce the experimental antishock effects on tissue perfusion and organ protection from fatal HS. |
format | Online Article Text |
id | pubmed-6927047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-69270472019-12-29 Electroacupuncture Improves the Survival Rate and Organ Function in a Rat Model of Hemorrhagic Shock Zhong, Yuxian Xu, Guochen Wu, Yushou Zhang, Huiping Wang, Haibin Ma, Liqian Zhang, Wenhua Yao, Yongming Wang, Lu Hu, Sen Litscher, Gerhard Evid Based Complement Alternat Med Research Article Electroacupuncture (EA) at ST36 can improve the survival rate in rats after hemorrhagic shock (HS). The current study investigated rats with 60% blood loss. 144 rats were divided into four groups: hemorrhage without fluid resuscitation (HS), EA after hemorrhage without fluid resuscitation (EA), hemorrhage with delayed resuscitation (DFR), and EA after hemorrhage with delayed resuscitation (EA + DFR). The survival rate and biological parameters 0, 3, 12, and 24 h after HS were investigated. The 24 h survival rate of EA + DFR was significantly higher than that of DFR. 12 h after hemorrhage, the level of mean arterial blood pressure of EA + DFR was significantly higher than that of DFR, and the levels of renal blood flow, intestinal mucosal blood flow, and hepatic blood flow of EA + DFR were also significantly higher than those of DFR. Three hours after hemorrhage, the levels of lactate, PaCO(2), alanine aminotransferase, and creatinine of groups receiving EA were significantly lower than those of non-EA groups, and the levels of pH, PaO(2), and diamine oxidase of groups receiving EA were significantly higher. EA at ST36 can improve the 24 h survival rate and produce the experimental antishock effects on tissue perfusion and organ protection from fatal HS. Hindawi 2019-12-11 /pmc/articles/PMC6927047/ /pubmed/31885667 http://dx.doi.org/10.1155/2019/8371862 Text en Copyright © 2019 Yuxian Zhong et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Zhong, Yuxian Xu, Guochen Wu, Yushou Zhang, Huiping Wang, Haibin Ma, Liqian Zhang, Wenhua Yao, Yongming Wang, Lu Hu, Sen Litscher, Gerhard Electroacupuncture Improves the Survival Rate and Organ Function in a Rat Model of Hemorrhagic Shock |
title | Electroacupuncture Improves the Survival Rate and Organ Function in a Rat Model of Hemorrhagic Shock |
title_full | Electroacupuncture Improves the Survival Rate and Organ Function in a Rat Model of Hemorrhagic Shock |
title_fullStr | Electroacupuncture Improves the Survival Rate and Organ Function in a Rat Model of Hemorrhagic Shock |
title_full_unstemmed | Electroacupuncture Improves the Survival Rate and Organ Function in a Rat Model of Hemorrhagic Shock |
title_short | Electroacupuncture Improves the Survival Rate and Organ Function in a Rat Model of Hemorrhagic Shock |
title_sort | electroacupuncture improves the survival rate and organ function in a rat model of hemorrhagic shock |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927047/ https://www.ncbi.nlm.nih.gov/pubmed/31885667 http://dx.doi.org/10.1155/2019/8371862 |
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