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RADAR: differential analysis of MeRIP-seq data with a random effect model
Epitranscriptome profiling using MeRIP-seq is a powerful technique for in vivo functional studies of reversible RNA modifications. We develop RADAR, a comprehensive analytical tool for detecting differentially methylated loci in MeRIP-seq data. RADAR enables accurate identification of altered methyl...
Autores principales: | Zhang, Zijie, Zhan, Qi, Eckert, Mark, Zhu, Allen, Chryplewicz, Agnieszka, De Jesus, Dario F., Ren, Decheng, Kulkarni, Rohit N., Lengyel, Ernst, He, Chuan, Chen, Mengjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927177/ https://www.ncbi.nlm.nih.gov/pubmed/31870409 http://dx.doi.org/10.1186/s13059-019-1915-9 |
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