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Combined but not single treatment with ethinylestradiol/levonorgestrel and spironolactone reduces plasminogen activator inhibitor-1 in insulin-resistant ovariectomised rats

OBJECTIVE: Increased circulating level of plasminogen activator inhibitor-1 (PAI-1) is associated with menopausal oestrogen deficiency. We therefore hypothesised that the combined oral contraceptive (COC) with spironolactone (SPL) improves insulin resistance (IR) in ovariectomised (OVX) rats by redu...

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Detalles Bibliográficos
Autores principales:	Aremu, Adeyanju Oluwaseun, Lilian, Dibia Chinaza, Olufemi, Soladoye Ayodele, Aderemi, Olatunji Lawrence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927203/ https://www.ncbi.nlm.nih.gov/pubmed/31856649 http://dx.doi.org/10.1177/1470320319895933

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