NUMB regulates the endocytosis and activity of the anaplastic lymphoma kinase in an isoform-specific manner

NUMB is an evolutionarily conserved protein that plays an important role in cell adhesion, migration, polarity, and cell fate determination. It has also been shown to play a role in the pathogenesis of certain cancers, although it remains controversial whether NUMB functions as an oncoprotein or tum...

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Detalles Bibliográficos
Autores principales: Wei, Ran, Liu, Xuguang, Voss, Courtney, Qin, Wentao, Dagnino, Lina, Li, Lei, Vigny, Marc, Li, Shawn Shun-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927325/
https://www.ncbi.nlm.nih.gov/pubmed/30726988
http://dx.doi.org/10.1093/jmcb/mjz003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927325/
https://www.ncbi.nlm.nih.gov/pubmed/30726988
http://dx.doi.org/10.1093/jmcb/mjz003

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