Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule

Progressive organ fibrosis accounts for one-third of all deaths worldwide, yet preclinical models that mimic the complex, progressive nature of the disease are lacking, and hence, there are no curative therapies. Progressive fibrosis across organs shares common cellular and molecular pathways involv...

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Detalles Bibliográficos
Autores principales: Vijayaraj, Preethi, Minasyan, Aspram, Durra, Abdo, Karumbayaram, Saravanan, Mehrabi, Mehrsa, Aros, Cody J., Ahadome, Sarah D., Shia, David W., Chung, Katherine, Sandlin, Jenna M., Darmawan, Kelly F., Bhatt, Kush V., Manze, Chase C., Paul, Manash K., Wilkinson, Dan C., Yan, Weihong, Clark, Amander T., Rickabaugh, Tammy M., Wallace, W. Dean, Graeber, Thomas G., Damoiseaux, Robert, Gomperts, Brigitte N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927560/
https://www.ncbi.nlm.nih.gov/pubmed/31825831
http://dx.doi.org/10.1016/j.celrep.2019.11.019

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