Self-association of human beta-galactocerebrosidase: Dependence on pH, salt, and surfactant

Krabbe disease, also known as globoid cell leukodystrophy, is a rare genetic neurodegenerative disease caused by a deficiency of the galactocerebrosidase enzyme. To understand the association status of human beta-galactocerebrosidase (hGALC) in solution, we employed analytical ultracentrifugation (A...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Eunhee, Salamat-Miller, Nazila, Stafford, Walter F., Taylor, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927645/
https://www.ncbi.nlm.nih.gov/pubmed/31869371
http://dx.doi.org/10.1371/journal.pone.0226618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927645/
https://www.ncbi.nlm.nih.gov/pubmed/31869371
http://dx.doi.org/10.1371/journal.pone.0226618

Ejemplares similares