Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level

Apoptosis is an essential defensive mechanism against tumorigenesis. Proteins of the B-cell lymphoma-2 (Bcl-2) family regulate programmed cell death by the mitochondrial apoptosis pathway. In response to intracellular stress, the apoptotic balance is governed by interactions of three distinct subgro...

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Detalles Bibliográficos
Autores principales: Kønig, Simon Mathis, Rissler, Vendela, Terkelsen, Thilde, Lambrughi, Matteo, Papaleo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927658/
https://www.ncbi.nlm.nih.gov/pubmed/31825969
http://dx.doi.org/10.1371/journal.pcbi.1007485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927658/
https://www.ncbi.nlm.nih.gov/pubmed/31825969
http://dx.doi.org/10.1371/journal.pcbi.1007485

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