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Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level
Apoptosis is an essential defensive mechanism against tumorigenesis. Proteins of the B-cell lymphoma-2 (Bcl-2) family regulate programmed cell death by the mitochondrial apoptosis pathway. In response to intracellular stress, the apoptotic balance is governed by interactions of three distinct subgro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927658/ https://www.ncbi.nlm.nih.gov/pubmed/31825969 http://dx.doi.org/10.1371/journal.pcbi.1007485 |