BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics

Balanced transforming growth factor-beta (TGFβ)/bone morphogenetic protein (BMP)-signaling is essential for tissue formation and homeostasis. While gain in TGFβ signaling is often found in diseases, the underlying cellular mechanisms remain poorly defined. Here we show that the receptor BMP type 2 (...

Descripción completa

Detalles Bibliográficos
Autores principales: Hiepen, Christian, Jatzlau, Jerome, Hildebrandt, Susanne, Kampfrath, Branka, Goktas, Melis, Murgai, Arunima, Cuellar Camacho, Jose Luis, Haag, Rainer, Ruppert, Clemens, Sengle, Gerhard, Cavalcanti-Adam, Elisabetta Ada, Blank, Kerstin G., Knaus, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927666/
https://www.ncbi.nlm.nih.gov/pubmed/31826007
http://dx.doi.org/10.1371/journal.pbio.3000557

Ejemplares similares

Ejemplares similares