Cargando…

Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis

Neuronal morphogenesis requires multiple regulatory pathways to appropriately determine axonal and dendritic structures, thereby to enable the functional neural connectivity. Yet, however, the precise mechanisms and components that regulate neuronal morphogenesis are still largely unknown. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Woo, Youngsik, Kim, Soo Jeong, Suh, Bo Kyoung, Kwak, Yongdo, Jung, Hyun-Jin, Nhung, Truong Thi My, Mun, Dong Jin, Hong, Ji-Ho, Noh, Su-Jin, Kim, Seunghyun, Lee, Ahryoung, Baek, Seung Tae, Nguyen, Minh Dang, Choe, Youngshik, Park, Sang Ki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927744/ https://www.ncbi.nlm.nih.gov/pubmed/31815665 http://dx.doi.org/10.7554/eLife.50850

Ejemplares similares

Regulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration
por: Hong, Ji-Ho, et al.
Publicado: (2016)

Disrupted-in-schizophrenia 1 enhances the quality of circadian rhythm by stabilizing BMAL1
por: Lee, Su Been, et al.
Publicado: (2021)

Roles for Ndel1 in keratin organization and desmosome function
por: Kim, Yong-Bae, et al.
Publicado: (2021)

GSK‐3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility
por: Gao, Feng J., et al.
Publicado: (2015)

Ndel1 Promotes Axon Regeneration via Intermediate Filaments
por: Toth, Cory, et al.
Publicado: (2008)

Role of GSK3 Signaling in Neuronal Morphogenesis
por: Kim, Yun Tai, et al.
Publicado: (2011)

The Cytoskeletal Protein Ndel1 Regulates Dynamin 2 GTPase Activity
por: Chansard, Mathieu, et al.
Publicado: (2011)

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation
por: Shen, Weijun, et al.
Publicado: (2015)

Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
por: Kim, Soo Jeong, et al.
Publicado: (2022)

GSK-3β, FYN, and DYRK1A: Master Regulators in Neurodegenerative Pathways
por: Demuro, Stefania, et al.
Publicado: (2021)

Ndel1 modulates dynein activation in two distinct ways
por: Garrott, Sharon R, et al.
Publicado: (2023)

Expression and function of Ndel1 during the differentiation of neural stem cells induced by hippocampal exosomesticle
por: Li, Wen, et al.
Publicado: (2021)

Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule–actin crosstalk during neurodevelopment
por: Mun, Dong Jin, et al.
Publicado: (2023)

Ratiometric measurement of MAM Ca(2+) dynamics using a modified CalfluxVTN
por: Cho, Eunbyul, et al.
Publicado: (2023)

Nde1 and Ndel1: Outstanding Mysteries in Dynein-Mediated Transport
por: Garrott, Sharon R., et al.
Publicado: (2022)

mTOR regulates brain morphogenesis by mediating GSK3 signaling
por: Ka, Minhan, et al.
Publicado: (2014)

Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β
por: Park, Jin-Hee, et al.
Publicado: (2023)

NDE1 and NDEL1: Multimerisation, alternate splicing and DISC1 interaction
por: Bradshaw, Nicholas J., et al.
Publicado: (2009)

LIS1 and NDEL1 Regulate Axonal Trafficking of Mitochondria in Mature Neurons
por: Pandey, Jai P., et al.
Publicado: (2022)

Conserved Roles for the Dynein Intermediate Chain and Ndel1 in Assembly and Activation of Dynein
por: Okada, Kyoko, et al.
Publicado: (2023)

Conserved roles for the dynein intermediate chain and Ndel1 in assembly and activation of dynein
por: Okada, Kyoko, et al.
Publicado: (2023)

Behavioral Deficits in Mice with Postnatal Disruption of Ndel1 in Forebrain Excitatory Neurons: Implications for Epilepsy and Neuropsychiatric Disorders
por: Gavrilovici, Cezar, et al.
Publicado: (2021)

Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex
por: Goo, Bon Seong, et al.
Publicado: (2022)

miR-103-3p targets Ndel1 to regulate neural stem cell proliferation and differentiation
por: Li, Wen, et al.
Publicado: (2021)

Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein–Aurora A pathway
por: Inaba, Hironori, et al.
Publicado: (2016)

The expression and roles of Nde1 and Ndel1 in the adult mammalian central nervous system
por: Pei, Z., et al.
Publicado: (2014)

Role of NDEL1 and VEGF/VEGFR-2 in Mouse Hippocampus After Status Epilepticus
por: Zhu, Lin, et al.
Publicado: (2020)

Ndel1 disfavors dynein–dynactin–adaptor complex formation in two distinct ways
por: Garrott, Sharon R., et al.
Publicado: (2023)

DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε
por: Weiss, Celine S., et al.
Publicado: (2013)

Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells
por: Hebbar, Sachin, et al.
Publicado: (2008)

Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon
por: Segal, Michal, et al.
Publicado: (2012)

Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150(glued)
por: Suh, Bo Kyoung, et al.
Publicado: (2021)

Inhibiting EGFR/HER-2 ameliorates neuroinflammatory responses and the early stage of tau pathology through DYRK1A
por: Kim, Jieun, et al.
Publicado: (2022)

Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A
por: Widowati, Esti Wahyu, et al.
Publicado: (2018)

The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein
por: Żyłkiewicz, Eliza, et al.
Publicado: (2011)

Evaluation of NDEL1 oligopeptidase activity in blood and brain in an animal model of schizophrenia: effects of psychostimulants and antipsychotics
por: Nani, João V., et al.
Publicado: (2020)

Aurora A phosphorylates Ndel1 to reduce the levels of Mad1 and NuMA at spindle poles
por: Janczyk, Paweł Ł., et al.
Publicado: (2022)

A novel de novo heterozygous DYRK1A mutation causes complete loss of DYRK1A function and developmental delay
por: Lee, Kyu-Sun, et al.
Publicado: (2020)

DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B
por: Yousefelahiyeh, Mina, et al.
Publicado: (2018)

Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B
por: Papenfuss, Marco, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vrl17sb0g4nrd2ottk6e7bfb4m