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Heparin chromatography as an in vitro predictor for antibody clearance rate through pinocytosis

The pharmacokinetic (PK) properties of therapeutic antibodies directly affect efficacy, dose and dose intervals, application route and tissue penetration. In indications where health-care providers and patients can choose between several efficacious and safe therapeutic options, convenience (determi...

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Detalles Bibliográficos
Autores principales:	Kraft, Thomas E., Richter, Wolfgang F., Emrich, Thomas, Knaupp, Alexander, Schuster, Michaela, Wolfert, Andreas, Kettenberger, Hubert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927760/ https://www.ncbi.nlm.nih.gov/pubmed/31769731 http://dx.doi.org/10.1080/19420862.2019.1683432

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