Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models

The development of antibody therapeutics relies on animal models that accurately recapitulate disease biology. Syngeneic mouse models are increasingly used with new molecules to capture the biology of complex cancers and disease states, and to provide insight into the role of the immune system. The...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Tsai, Jordan C., Davis, Jonathan H., Chau, Bryant, Dong, Jia, West, Sean M., Hogan, Jason M., Wheeler, Matthew L., Bee, Christine, Morishige, Winse, Cayton, Thomas, David-brown, Donata, Zhang, Chengyue, Kozhich, Alexander, Sproul, Tim, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927765/
https://www.ncbi.nlm.nih.gov/pubmed/31856660
http://dx.doi.org/10.1080/19420862.2019.1685350

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