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Rack1 Controls Parallel Fiber–Purkinje Cell Synaptogenesis and Synaptic Transmission

Purkinje cells (PCs) in the cerebellum receive two excitatory afferents including granule cells-derived parallel fiber (PF) and the climbing fiber. Scaffolding protein Rack1 is highly expressed in the cerebellar PCs. Here, we found delayed formation of specific cerebellar vermis lobule and impaired...

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Detalles Bibliográficos
Autores principales: Yang, Haihong, Yang, Chaojuan, Zhu, Qian, Wei, Mengping, Li, Ying, Cheng, Juanxian, Liu, Fengjiao, Wu, Yan, Zhang, Jiyan, Zhang, Chen, Wu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927999/
https://www.ncbi.nlm.nih.gov/pubmed/31920545
http://dx.doi.org/10.3389/fncel.2019.00539