Genetic diversity of respiratory enteroviruses and rhinoviruses in febrile adults, Singapore, 2007‐2013

To understand the genetic diversity and patterns of circulation of rhinoviruses (RV) and enteroviruses (EV) in Singapore, we retrospectively screened 2950 nasal swab samples collected from adults presenting to primary care services with signs of febrile illness in Singapore during 2007‐2013 using se...

Descripción completa

Detalles Bibliográficos
Autores principales: Linster, Martin, Donato, Celeste, Mah, Marcus G., Grau, Miguel L., Low, Jenny G., Ooi, Eng Eong, Su, Yvonne C.F., Smith, Gavin J.D., Vijaykrishna, Dhanasekaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Short Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928033/
https://www.ncbi.nlm.nih.gov/pubmed/31568667
http://dx.doi.org/10.1111/irv.12662
Descripción
Sumario:To understand the genetic diversity and patterns of circulation of rhinoviruses (RV) and enteroviruses (EV) in Singapore, we retrospectively screened 2950 nasal swab samples collected from adults presenting to primary care services with signs of febrile illness in Singapore during 2007‐2013 using sequencing and phylogenetic methods. Through sequencing and phylogenetic analysis, our results show the year‐round circulation of the three rhinovirus species, A, B, and C. A diverse set of RV/EV serotypes were detected in Singapore with a predominance of RV‐A in all years, whereas serotypes EV‐C A21 and EV‐D68 were only sporadically detected. This study highlights the previously unrecognized diversity and burden in the adult population in Singapore.

Ejemplares similares