Perturbation of Ephrin Receptor Signaling and Glutamatergic Transmission in the Hypothalamus in Depression Using Proteomics Integrated With Metabolomics

Hypothalamic dysfunction is a key pathological factor in inflammation-associated depression. In the present study, isobaric tags for relative-absolute quantitation (iTRAQ) combined with mass spectrometry and gas chromatography-mass spectrometry (GC-MS) were employed to detect the proteomes and metab...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Wei, Zhenhong, Li, Yonghong, Wei, Chaojun, Li, Yuanting, Cheng, Pengfei, Xu, Hui, Li, Zhenhao, Guo, Rui, Qi, Xiaoming, Jia, Jing, Jia, Yanjuan, Wang, Wanxia, Gao, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928102/
https://www.ncbi.nlm.nih.gov/pubmed/31920518
http://dx.doi.org/10.3389/fnins.2019.01359

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