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Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes

Sideroflexin4 (SFXN4) is a member of a family of nuclear-encoded mitochondrial proteins. Rare germline mutations in SFXN4 lead to phenotypic characteristics of mitochondrial disease including impaired mitochondrial respiration and hematopoetic abnormalities. We sought to explore the function of this...

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Detalles Bibliográficos
Autores principales:	Paul, Bibbin T., Tesfay, Lia, Winkler, C. R., Torti, Frank M., Torti, Suzy V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928202/ https://www.ncbi.nlm.nih.gov/pubmed/31873120 http://dx.doi.org/10.1038/s41598-019-55907-z

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